Elevated PSA

What is PSA? Elevated prostate-specific antigen (PSA) is a protein that is created by normal cells, as well as malignant cells of the prostate gland.

While PSA is mostly found in semen, which also is produced in the prostate, small amounts of PSA ordinarily circulate in the blood.

The PSA test can detect high levels of PSA in the blood that may indicate the presence of prostate cancer. It can also indicate noncancerous problems such as prostate enlargement (BPH) and inflammation.

Why do I need this test? Prostate cancer is a frequent cause of cancer death. Early detection may be a crucial tool in getting appropriate and timely treatment.

The PSA test can be a great tool to find signs of prostate cancer, however, it does not provide precise diagnostic information about the condition of the prostate.

The PSA test is only one tool used to screen for early signs of prostate cancer. Another common screening test, usually done in addition to a PSA test, is a transrectal ultrasound.

What happens if I have abnormal results? Neither the PSA test nor the digital rectal exam provides enough information for our urologist to diagnose prostate cancer. Abnormal results in these tests may lead our doctor to recommend a prostate biopsy to further investigate this.

During a prostate biopsy, samples of prostate tissue are removed for laboratory examination. A diagnosis of cancer is based on the biopsy results.

Medical organizations vary in their recommendations about who should — and who shouldn't — get a PSA screening test. Discussing with your doctor the benefits, limitations and potential risks of the PSA test can help you make an informed decision.